Monday, February 16, 2009

What the Studies tell about the Cat let we know

The Canadian American Ticlopidine Study (CATS) in thromboembolic stroke. Design, organization, and baseline results
M Gent, JA Blakely, JD Easton, DJ Ellis, VC Hachinski, JW Harbison, E Panak, RS Roberts, J Sicurella and AG Turpie Faculty of Health Sciences, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.
The Canadian American Ticlopidine Study is a randomized, placebo- controlled, double-blind, multicenter study to assess the efficacy and safety of ticlopidine hydrochloride in patients who have suffered a thromboembolic stroke no less than 1 week and no more than 4 months before entry into the study. The primary assessment of efficacy will be based on the cluster of outcome events recurrent stroke, myocardial infarction, or vascular death. Twenty-five clinical centers, 12 in Canada and 13 in the United States, entered a total of 1,072 patients during a 3-year recruitment period; these patients were randomly allocated to receive either 250 mg ticlopidine or identical-appearing placebo tablets twice daily for up to 3 years. Patient recruitment was completed in December 1986. Patients were followed for a maximum of 3 years or until the close of the study in December 1987; at that time an average follow-up of 25 months had been achieved. We summarize the protocol and organization of the study and document the methods of execution and analysis, with corresponding criteria, before disclosure of the treatment code to any of the study investigators. We also provide a clinical description of the patients at entry into the study.

CATS LIFE


The cat (Felis catus), also known as the domestic cat or house cat to distinguish it from other felines and felids, is a small predatory carnivorous species of crepuscular mammal that is valued by humans for its companionship and its ability to hunt vermin, snakes, scorpions and other unwanted household pests. It has been associated with humans for at least 9,500 years.[5]
A skilled predator, the cat is known to hunt over 1,000 species for food. It can be trained to obey simple commands. Individual cats have also been known to learn on their own to manipulate simple mechanisms, such as doorknobs. Cats use a variety of vocalizations and types of body language for communication, including meowing, purring, hissing, growling, squeaking, chirping, clicking, and grunting.[6] Cats may be the most popular pet in the world, with over 600 million in homes all over the world.[7] They are also bred and shown as registered pedigree pets. This hobby is known as the "cat fancy."

Animals


Animals are a major group of multicellular, eukaryotic organisms of the kingdom Animalia or Metazoa. Their body plan eventually becomes fixed as they develop, although some undergo a process of metamorphosis later on in their life. Most animals are motile, meaning they can move spontaneously and independently. Animals are also heterotrophs, meaning they must ingest other organisms for sustenance.
Most known animal phyla appeared in the fossil record as marine species during the
Cambrian explosion, about 542 million years ago